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Antitumor Efficacy of Human Monocyte-Derived Dendritic Cells: Comparing Effects of two Monocyte Isolation Methods

BACKGROUND: Dendritic cells (DCs), which can be used as anti-cancer vaccines, are generally obtained in vitro from isolated CD14(+) monocytes (MoDCs). This generates high cell numbers and allows instructing DCs to guarantee effective antitumor responses. However, the impact of the monocyte isolation...

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Detalles Bibliográficos
Autores principales: Marques, Graça S, Silva, Zélia, Videira, Paula A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796591/
https://www.ncbi.nlm.nih.gov/pubmed/29434528
http://dx.doi.org/10.1186/s12575-018-0069-6