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Rebound excitability mediates motor abnormalities in Parkinson’s disease
Parkinson’s disease (PD) is a debilitating disorder resulting from loss of dopamine neurons. In dopamine deficient state, the basal ganglia increases inhibitory synaptic outputs to the thalamus. This increased inhibition by the basal ganglia output is known to reduce firing rate of thalamic neurons...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796627/ https://www.ncbi.nlm.nih.gov/pubmed/29335072 http://dx.doi.org/10.5483/BMBRep.2018.51.1.004 |