Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug

Polycomb group (PcG) proteinB lymphoma Mo-MLV insertion region 1 homolog (BMI1) is a transcriptional repressor that plays an important role in human carcinogenesis. MicroRNAs (miRNAs) are endogenous small non-coding RNAsthat implicate a negative regulation on gene expression. Deregulation of the exp...

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Detalles Bibliográficos
Autores principales: Patel, Nibedita, Garikapati, Koteswara Rao, Makani, Venkata Krishna Kanth, Nair, Ayikkara Drishya, Vangara, Namratha, Bhadra, Utpal, Pal Bhadra, Manika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796693/
https://www.ncbi.nlm.nih.gov/pubmed/29394261
http://dx.doi.org/10.1371/journal.pone.0190245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796693/
https://www.ncbi.nlm.nih.gov/pubmed/29394261
http://dx.doi.org/10.1371/journal.pone.0190245

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