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Functional analysis of the C. elegans cyld-1 gene reveals extensive similarity with its human homolog

The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that include the regulation of several cell growth, differe...

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Detalles Bibliográficos
Autores principales: Hadweh, Paul, Chaitoglou, Iro, Gravato-Nobre, Maria Joao, Ligoxygakis, Petros, Mosialos, George, Hatzivassiliou, Eudoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796713/
https://www.ncbi.nlm.nih.gov/pubmed/29394249
http://dx.doi.org/10.1371/journal.pone.0191864