MHC Intratumoral Heterogeneity May Predict Cancer Progression and Response to Immunotherapy

An individual tumor can present intratumoral phenotypic heterogeneity, containing tumor cells with different phenotypes that do not present irreversible genetic alterations. We have developed a mouse cancer model, named GR9, derived from a methylcholanthrene-induced fibrosarcoma that was adapted to...

Descripción completa

Detalles Bibliográficos
Autores principales: Romero, Irene, Garrido, Cristina, Algarra, Ignacio, Chamorro, Virginia, Collado, Antonia, Garrido, Federico, Garcia-Lora, Angel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796886/
https://www.ncbi.nlm.nih.gov/pubmed/29434605
http://dx.doi.org/10.3389/fimmu.2018.00102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796886/
https://www.ncbi.nlm.nih.gov/pubmed/29434605
http://dx.doi.org/10.3389/fimmu.2018.00102

Ejemplares similares