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MHC Intratumoral Heterogeneity May Predict Cancer Progression and Response to Immunotherapy
An individual tumor can present intratumoral phenotypic heterogeneity, containing tumor cells with different phenotypes that do not present irreversible genetic alterations. We have developed a mouse cancer model, named GR9, derived from a methylcholanthrene-induced fibrosarcoma that was adapted to...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796886/ https://www.ncbi.nlm.nih.gov/pubmed/29434605 http://dx.doi.org/10.3389/fimmu.2018.00102 |