Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways

CREB (cAMP Response Element Binding protein) is a transcription factor that is overexpressed in primary acute myeloid leukemia (AML) cells and associated with a decreased event-free survival and increased risk of relapse. We recently reported a small molecule inhibitor of CREB, XX-650-23, which inhi...

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Detalles Bibliográficos
Autores principales: Chae, Hee-Don, Cox, Nick, Dahl, Gary V., Lacayo, Norman J., Davis, Kara L., Capolicchio, Samanta, Smith, Mark, Sakamoto, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796975/
https://www.ncbi.nlm.nih.gov/pubmed/29435104
http://dx.doi.org/10.18632/oncotarget.23794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796975/
https://www.ncbi.nlm.nih.gov/pubmed/29435104
http://dx.doi.org/10.18632/oncotarget.23794

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