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Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia

We previously reported that microRNA (miR)-29b is down-regulated and has a tumor suppressor role in acute myeloid leukemia (AML). However, little is known about the mechanisms responsible for miR-29b expression downregulation in AML. In this work we screened for mutations that could affect miR-29b e...

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Detalles Bibliográficos
Autores principales: Ngankeu, Apollinaire, Ranganathan, Parvathi, Havelange, Violaine, Nicolet, Deedra, Volinia, Stefano, Powell, Bayard L., Kolitz, Jonathan E., Uy, Geoffrey L., Stone, Richard M., Kornblau, Steven M., Andreeff, Michael, Croce, Carlo M., Bloomfield, Clara D., Garzon, Ramiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796978/
https://www.ncbi.nlm.nih.gov/pubmed/29435107
http://dx.doi.org/10.18632/oncotarget.23150