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Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer
DNA methylation is important for gene expression and genome stability, and its disruption is thought to play a key role in the initiation and progression of cancer and other diseases. The DLK1-DIO3 cluster has been shown to be imprinted in humans, and some of its components are relevant to diverse p...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796982/ https://www.ncbi.nlm.nih.gov/pubmed/29435111 http://dx.doi.org/10.18632/oncotarget.10611 |