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RAS GTPases are modified by SUMOylation

RAS proteins are GTPases that participate in multiple signal cascades, regulating crucial cellular processes including cell survival, proliferation, differentiation, and autophagy. Mutations or deregulated activities of RAS are frequently the driving force for oncogenic transformation and tumorigene...

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Detalles Bibliográficos
Autores principales: Choi, Byeong Hyeok, Chen, Changyan, Philips, Mark, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796985/
https://www.ncbi.nlm.nih.gov/pubmed/29435114
http://dx.doi.org/10.18632/oncotarget.23269