The inhibition of PLCγ1 protects chondrocytes against osteoarthritis, implicating its binding to Akt

Previous studies have addressed the involvement of phosphoinositide-specifc phospholipase γ1 (PLCγ1) and protein kinase B (PKB/Akt) in osteoarthritis (OA) pathogenesis, but it is not ascertained the possibility of them to be potential targets for OA therapy. Here, through local intra-articular injec...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Heguo, Qu, Ning, Chen, Xiaolei, Zhou, Yang, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796987/
https://www.ncbi.nlm.nih.gov/pubmed/29435116
http://dx.doi.org/10.18632/oncotarget.23286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796987/
https://www.ncbi.nlm.nih.gov/pubmed/29435116
http://dx.doi.org/10.18632/oncotarget.23286

Ejemplares similares