APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response

APOBEC enzymes are responsible for a mutation signature (TCW>T/G) implicated in a wide variety of tumors. We explore the APOBEC mutational signature in bladder cancer and the relationship with specific mutations, molecular subtype, gene expression, and survival using sequencing data from The Canc...

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Detalles Bibliográficos
Autores principales: Glaser, Alexander P., Fantini, Damiano, Wang, Yiduo, Yu, Yanni, Rimar, Kalen J., Podojil, Joseph R., Miller, Stephen D., Meeks, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796993/
https://www.ncbi.nlm.nih.gov/pubmed/29435122
http://dx.doi.org/10.18632/oncotarget.23344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796993/
https://www.ncbi.nlm.nih.gov/pubmed/29435122
http://dx.doi.org/10.18632/oncotarget.23344

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