Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis

Upon sunitinib treatment of metastatic renal cell carcinoma patients eventually acquire resistance. Our aim was to investigate microRNAs behind sunitinib resistance. We developed an in vivo xenograft and an in vitro model and compared morphological, immunhistochemical, transcriptomical and miRNome d...

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Detalles Bibliográficos
Autores principales: Butz, Henriett, Ding, Qiang, Nofech-Mozes, Roy, Lichner, Zsuzsanna, Ni, Heyu, Yousef, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797004/
https://www.ncbi.nlm.nih.gov/pubmed/29435133
http://dx.doi.org/10.18632/oncotarget.23163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797004/
https://www.ncbi.nlm.nih.gov/pubmed/29435133
http://dx.doi.org/10.18632/oncotarget.23163

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