Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing

Drug repurposing approaches have the potential advantage of facilitating rapid and cost-effective development of new therapies. Particularly, the repurposing of drugs with known safety profiles in children could bypass or streamline toxicity studies. We employed a phenotypic screening paradigm on a...

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Detalles Bibliográficos
Autores principales: Shen, Min, Asawa, Rosita, Zhang, Ya-Qin, Cunningham, Elizabeth, Sun, Hongmao, Tropsha, Alexander, Janzen, William P., Muratov, Eugene N., Capuzzi, Stephen J., Farag, Sherif, Jadhav, Ajit, Blatt, Julie, Simeonov, Anton, Martinez, Natalia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797010/
https://www.ncbi.nlm.nih.gov/pubmed/29435139
http://dx.doi.org/10.18632/oncotarget.23462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797010/
https://www.ncbi.nlm.nih.gov/pubmed/29435139
http://dx.doi.org/10.18632/oncotarget.23462

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