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Co-expression analysis revealed PTCH1-3'UTR promoted cell migration and invasion by activating miR-101-3p/SLC39A6 axis in non-small cell lung cancer: implicating the novel function of PTCH1

Metastasis is the most common cause of mortality for non-small cell lung cancer (NSCLC). PTCH1, a receptor of Hedgehog (Hh) pathway, is reported to suppress cell proliferation. Interestingly, our previous study showed PTCH1 silencing promoted cell proliferation but inhibited cell migration and invas...

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Detalles Bibliográficos
Autores principales: Wan, Xuechao, Kong, Zhe, Chu, Kaili, Yi, Chuanyou, Hu, Jian, Qin, Rui, Zhao, Chen, Fu, Fangqiu, Wu, Hai, Li, Yao, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797013/
https://www.ncbi.nlm.nih.gov/pubmed/29435142
http://dx.doi.org/10.18632/oncotarget.23219