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TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

Although the mechanisms of Tumor necrosis factor alpha (TNF-α) on facilitating osteoclast differentiation and bone resorption is well known, the mechanisms behind the suppression of the osteoblast differentiation from mesenchymal stem cells (MSCs) are still poorly understood. In this study, we obser...

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Detalles Bibliográficos
Autores principales: Zuo, Chijian, Zhao, Xiaoying, Shi, Yu, Wu, Wen, Zhang, Ning, Xu, Jiake, Wang, Chuandong, Hu, Guoli, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797016/
https://www.ncbi.nlm.nih.gov/pubmed/29435145
http://dx.doi.org/10.18632/oncotarget.23373