Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer

The MYC transcription factor coordinates, via different RNA polymerases, the transcription of both ribosomal RNA (rRNA) and protein genes necessary for nucleolar as well as mitochondrial ribogenesis. In this study we tested if MYC-coordination of rRNA transcription in the nucleolus and in the mitoch...

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Detalles Bibliográficos
Autores principales: Rossetti, Stefano, Wierzbicki, Andrzej J., Sacchi, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797030/
https://www.ncbi.nlm.nih.gov/pubmed/29435159
http://dx.doi.org/10.18632/oncotarget.23579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797030/
https://www.ncbi.nlm.nih.gov/pubmed/29435159
http://dx.doi.org/10.18632/oncotarget.23579

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