Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

DNA hypomethylation coordinately targets various signaling pathways involved in tumor growth and metastasis. At present, there are no approved therapeutic modalities that target hypomethylation. In this regard, we examined the therapeutic plausibility of using universal methyl group donor S-adenosyl...

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Detalles Bibliográficos
Autores principales: Mahmood, Niaz, Cheishvili, David, Arakelian, Ani, Tanvir, Imrana, Khan, Haseeb Ahmed, Pépin, Anne-Sophie, Szyf, Moshe, Rabbani, Shafaat A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797041/
https://www.ncbi.nlm.nih.gov/pubmed/29435170
http://dx.doi.org/10.18632/oncotarget.23704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797041/
https://www.ncbi.nlm.nih.gov/pubmed/29435170
http://dx.doi.org/10.18632/oncotarget.23704

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