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New cGMP analogues restrain proliferation and migration of melanoma cells

Melanoma is one of the most aggressive cancers and displays high resistance to conventional chemotherapy underlining the need for new therapeutic strategies. The cGMP/PKG signaling pathway was detected in melanoma cells and shown to reduce migration, proliferation and to increase apoptosis in differ...

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Detalles Bibliográficos
Autores principales: Vighi, Eleonora, Rentsch, Andreas, Henning, Philipp, Comitato, Antonella, Hoffmann, Dorit, Bertinetti, Daniela, Bertolotti, Evelina, Schwede, Frank, Herberg, Friedrich W., Genieser, Hans-Gottfried, Marigo, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797051/
https://www.ncbi.nlm.nih.gov/pubmed/29435180
http://dx.doi.org/10.18632/oncotarget.23685