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Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway

As an endocrine disease, type 2 diabetes mellitus (T2DM) can cause testicular damage which induces male infertility. However, the underlying mechanism is still not clear. We prove that T2DM induced testicular microcirculation impairment involves the decrease of VEGF and these actions are regulated b...

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Detalles Bibliográficos
Autores principales: Long, Lingli, Qiu, Han, Cai, Bing, Chen, Ningning, Lu, Xiaofang, Zheng, Shuhui, Ye, Xiaoxin, Li, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797052/
https://www.ncbi.nlm.nih.gov/pubmed/29435181
http://dx.doi.org/10.18632/oncotarget.23915