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Hyperglycemia induced testicular damage in type 2 diabetes mellitus rats exhibiting microcirculation impairments associated with vascular endothelial growth factor decreased via PI3K/Akt pathway
As an endocrine disease, type 2 diabetes mellitus (T2DM) can cause testicular damage which induces male infertility. However, the underlying mechanism is still not clear. We prove that T2DM induced testicular microcirculation impairment involves the decrease of VEGF and these actions are regulated b...
Autores principales: | Long, Lingli, Qiu, Han, Cai, Bing, Chen, Ningning, Lu, Xiaofang, Zheng, Shuhui, Ye, Xiaoxin, Li, Yubin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797052/ https://www.ncbi.nlm.nih.gov/pubmed/29435181 http://dx.doi.org/10.18632/oncotarget.23915 |
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