Replication confers β cell immaturity

Pancreatic β cells are highly specialized to regulate systemic glucose levels by secreting insulin. In adults, increase in β-cell mass is limited due to brakes on cell replication. In contrast, proliferation is robust in neonatal β cells that are functionally immature as defined by a lower set point...

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Detalles Bibliográficos
Autores principales: Puri, Sapna, Roy, Nilotpal, Russ, Holger A., Leonhardt, Laura, French, Esra K., Roy, Ritu, Bengtsson, Henrik, Scott, Donald K., Stewart, Andrew F., Hebrok, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797102/
https://www.ncbi.nlm.nih.gov/pubmed/29396395
http://dx.doi.org/10.1038/s41467-018-02939-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797102/
https://www.ncbi.nlm.nih.gov/pubmed/29396395
http://dx.doi.org/10.1038/s41467-018-02939-0

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