Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening

Currently, many strains of influenza A virus have developed resistance against anti-influenza drugs, and it is essential to find new chemicals to combat this virus. The influenza polymerase with three proteins, PA, PB1 and PB2, is a crucial component of the viral ribonucleoprotein (RNP) complex. Her...

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Detalles Bibliográficos
Autores principales: Lo, Chun-Yeung, Li, Olive Tin-Wai, Tang, Wen-Ping, Hu, Chun, Wang, Guo Xin, Ngo, Jacky Chi-Ki, Wan, David Chi-Cheong, Poon, Leo Lit-Man, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797126/
https://www.ncbi.nlm.nih.gov/pubmed/29396435
http://dx.doi.org/10.1038/s41598-018-20772-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797126/
https://www.ncbi.nlm.nih.gov/pubmed/29396435
http://dx.doi.org/10.1038/s41598-018-20772-9

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