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Gene therapy for human glioblastoma using neurotropic JC virus-like particles as a gene delivery vector

Glioblastoma multiforme (GBM), the most common malignant brain tumor, has a short period of survival even with recent multimodality treatment. The neurotropic JC polyomavirus (JCPyV) infects glial cells and oligodendrocytes and causes fatal progressive multifocal leukoencephalopathy in patients with...

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Detalles Bibliográficos
Autores principales: Chao, Chun-Nun, Yang, Yu-Hsuan, Wu, Mu-Sheng, Chou, Ming-Chieh, Fang, Chiung-Yao, Lin, Mien-Chun, Tai, Chien-Kuo, Shen, Cheng-Huang, Chen, Pei-Lain, Chang, Deching, Wang, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797127/
https://www.ncbi.nlm.nih.gov/pubmed/29396437
http://dx.doi.org/10.1038/s41598-018-19825-w