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Repeated five-day administration of L-BMAA, microcystin-LR, or as mixture, in adult C57BL/6 mice - lack of adverse cognitive effects

The cyanobacterial toxins β-methylamino-L-alanine (L-BMAA) and microcystin-LR (MC-LR; a potent liver toxin) are suspected to cause neurological disorders. Adult male C57BL/6JOlaHsd mice aged approximately 11 months were subcutaneously injected for five consecutive days with L-BMAA and microcystin-LR...

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Detalles Bibliográficos
Autores principales: Myhre, Oddvar, Eide, Dag Marcus, Kleiven, Synne, Utkilen, Hans Christian, Hofer, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797144/
https://www.ncbi.nlm.nih.gov/pubmed/29396538
http://dx.doi.org/10.1038/s41598-018-20327-y