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TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin

The delivery of hydrophilic macromolecules runs into difficulties such as penetration of the cell membrane lipid bilayer. Our prior experiment demonstrated that capsaicin induces the reversible opening of tight junctions (TJs) and enhances the delivery of hydrophilic macromolecules through a paracel...

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Detalles Bibliográficos
Autores principales: Kanda, Yusuke, Yamasaki, Youhei, Sasaki-Yamaguchi, Yoshie, Ida-Koga, Noriko, Kamisuki, Shinji, Sugawara, Fumio, Nagumo, Yoko, Usui, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797179/
https://www.ncbi.nlm.nih.gov/pubmed/29396565
http://dx.doi.org/10.1038/s41598-018-20526-7