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TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin
The delivery of hydrophilic macromolecules runs into difficulties such as penetration of the cell membrane lipid bilayer. Our prior experiment demonstrated that capsaicin induces the reversible opening of tight junctions (TJs) and enhances the delivery of hydrophilic macromolecules through a paracel...
Autores principales: | Kanda, Yusuke, Yamasaki, Youhei, Sasaki-Yamaguchi, Yoshie, Ida-Koga, Noriko, Kamisuki, Shinji, Sugawara, Fumio, Nagumo, Yoko, Usui, Takeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797179/ https://www.ncbi.nlm.nih.gov/pubmed/29396565 http://dx.doi.org/10.1038/s41598-018-20526-7 |
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