Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

The scaffold protein DLGAP1 is localized at the post-synaptic density (PSD) of glutamatergic neurons and is a component of supramolecular protein complexes organized by PSD95. Gain-of-function variants of DLGAP1 have been associated with obsessive-compulsive disorder (OCD), while haploinsufficient v...

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Detalles Bibliográficos
Autores principales: Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A., Dulawa, S. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797244/
https://www.ncbi.nlm.nih.gov/pubmed/29396406
http://dx.doi.org/10.1038/s41598-018-20610-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797244/
https://www.ncbi.nlm.nih.gov/pubmed/29396406
http://dx.doi.org/10.1038/s41598-018-20610-y

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