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Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

The scaffold protein DLGAP1 is localized at the post-synaptic density (PSD) of glutamatergic neurons and is a component of supramolecular protein complexes organized by PSD95. Gain-of-function variants of DLGAP1 have been associated with obsessive-compulsive disorder (OCD), while haploinsufficient v...

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Detalles Bibliográficos
Autores principales:	Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A., Dulawa, S. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797244/ https://www.ncbi.nlm.nih.gov/pubmed/29396406 http://dx.doi.org/10.1038/s41598-018-20610-y

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