92R Monoclonal Antibody Inhibits Human CCR9(+) Leukemia Cells Growth in NSG Mice Xenografts

CCR9 is as an interesting target for the treatment of human CCR9(+)-T cell acute lymphoblastic leukemia, since its expression is limited to immature cells in the thymus, infiltrating leukocytes in the small intestine and a small fraction of mature circulating T lymphocytes. 92R, a new mouse mAb (IgG...

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Detalles Bibliográficos
Autores principales: Somovilla-Crespo, Beatriz, Martín Monzón, Maria Teresa, Vela, Maria, Corraliza-Gorjón, Isabel, Santamaria, Silvia, Garcia-Sanz, Jose A., Kremer, Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797297/
https://www.ncbi.nlm.nih.gov/pubmed/29434597
http://dx.doi.org/10.3389/fimmu.2018.00077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797297/
https://www.ncbi.nlm.nih.gov/pubmed/29434597
http://dx.doi.org/10.3389/fimmu.2018.00077

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