Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences

BACKGROUND: Surfactant Protein-A (SP-A) is a major protein component of surfactant and plays a role in surfactant-related functions and innate immunity. Human SP-A consists of two functional genes, SFTPA1 and SFTPA2, encoding SP-A1 and SP-A2 proteins, respectively and each is identified with numerou...

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Detalles Bibliográficos
Autores principales: Thorenoor, Nithyananda, Zhang, Xuesheng, Umstead, Todd M., Scott Halstead, E., Phelps, David S., Floros, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797374/
https://www.ncbi.nlm.nih.gov/pubmed/29394894
http://dx.doi.org/10.1186/s12931-018-0723-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797374/
https://www.ncbi.nlm.nih.gov/pubmed/29394894
http://dx.doi.org/10.1186/s12931-018-0723-1

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