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Interleukin-6 and Interferon-α Signaling via JAK1–STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States

Malignancy-induced alterations to cytokine signaling in tumor cells differentially regulate their interactions with the immune system and oncolytic viruses. The abundance of inflammatory cytokines in the tumor microenvironment suggests that such signaling plays key roles in tumor development and the...

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Detalles Bibliográficos
Autores principales: Danziger, Oded, Pupko, Tal, Bacharach, Eran, Ehrlich, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797546/
https://www.ncbi.nlm.nih.gov/pubmed/29441069
http://dx.doi.org/10.3389/fimmu.2018.00094