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Interleukin-6 and Interferon-α Signaling via JAK1–STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States
Malignancy-induced alterations to cytokine signaling in tumor cells differentially regulate their interactions with the immune system and oncolytic viruses. The abundance of inflammatory cytokines in the tumor microenvironment suggests that such signaling plays key roles in tumor development and the...
Autores principales: | Danziger, Oded, Pupko, Tal, Bacharach, Eran, Ehrlich, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797546/ https://www.ncbi.nlm.nih.gov/pubmed/29441069 http://dx.doi.org/10.3389/fimmu.2018.00094 |
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