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α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise

The loss of protein homeostasis that has been associated with aging leads to altered levels and conformational instability of proteins, which tend to form toxic aggregates. In particular, brain aging presents characteristic patterns of misfolded oligomers, primarily constituted of β-amyloid (Aβ), ta...

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Detalles Bibliográficos
Autores principales: Daniele, Simona, Pietrobono, Deborah, Fusi, Jonathan, Lo Gerfo, Annalisa, Cerri, Eugenio, Chico, Lucia, Iofrida, Caterina, Petrozzi, Lucia, Baldacci, Filippo, Giacomelli, Chiara, Galetta, Fabio, Siciliano, Gabriele, Bonuccelli, Ubaldo, Trincavelli, Maria L., Franzoni, Ferdinando, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797553/
https://www.ncbi.nlm.nih.gov/pubmed/29441013
http://dx.doi.org/10.3389/fnagi.2018.00017