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Adipocyte Fatty Acid-Binding Protein Promotes Palmitate-Induced Mitochondrial Dysfunction and Apoptosis in Macrophages

A high level of circulating free fatty acids (FFAs) is known to be an important trigger for macrophage apoptosis during the development of atherosclerosis. However, the underlying mechanism by which FFAs result in macrophage apoptosis is not well understood. In cultured human macrophage Thp-1 cells,...

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Detalles Bibliográficos
Autores principales: Li, Hui, Xiao, Yang, Tang, Lin, Zhong, Feng, Huang, Gan, Xu, Jun-Mei, Xu, Ai-Min, Dai, Ru-Ping, Zhou, Zhi-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797554/
https://www.ncbi.nlm.nih.gov/pubmed/29441065
http://dx.doi.org/10.3389/fimmu.2018.00081