Cargando…
Adipocyte Fatty Acid-Binding Protein Promotes Palmitate-Induced Mitochondrial Dysfunction and Apoptosis in Macrophages
A high level of circulating free fatty acids (FFAs) is known to be an important trigger for macrophage apoptosis during the development of atherosclerosis. However, the underlying mechanism by which FFAs result in macrophage apoptosis is not well understood. In cultured human macrophage Thp-1 cells,...
Autores principales: | Li, Hui, Xiao, Yang, Tang, Lin, Zhong, Feng, Huang, Gan, Xu, Jun-Mei, Xu, Ai-Min, Dai, Ru-Ping, Zhou, Zhi-Guang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797554/ https://www.ncbi.nlm.nih.gov/pubmed/29441065 http://dx.doi.org/10.3389/fimmu.2018.00081 |
Ejemplares similares
-
Adipocyte Fatty Acid-Binding Protein, Cardiovascular Diseases and Mortality
por: Lee, Chi-Ho, et al.
Publicado: (2021) -
IGF‑1 inhibits palmitic acid‑induced mitochondrial apoptosis in macrophages
por: Tang, Wanying, et al.
Publicado: (2023) -
Atlas of metabolism reveals palmitic acid results in mitochondrial dysfunction and cell apoptosis by inhibiting fatty acid β-oxidation in Sertoli cells
por: Xu, Xiaoqin, et al.
Publicado: (2022) -
Macrophage and Adipocyte Mitochondrial Dysfunction in Obesity-Induced Metabolic Diseases
por: Wang, Liwen, et al.
Publicado: (2021) -
Mitochondrial dysfunction and activation of iNOS are responsible for the palmitate-induced decrease in adiponectin synthesis in 3T3L1 adipocytes
por: Jeon, Min Jae, et al.
Publicado: (2012)