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Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis

Despite advances, identification and formulation of safe and effective vaccine for long-lasting protection against leishmaniasis is still inadequate. In this study, we have identified a novel antigen, leishmanial elongation factor-1α (EF1-α), as an immunodominant component of solubilized leishmanial...

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Detalles Bibliográficos
Autores principales: Sabur, Abdus, Bhowmick, Sudipta, Chhajer, Rudra, Ejazi, Sarfaraz Ahmad, Didwania, Nicky, Asad, Mohammad, Bhattacharyya, Anirban, Sinha, Utsa, Ali, Nahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797590/
https://www.ncbi.nlm.nih.gov/pubmed/29441060
http://dx.doi.org/10.3389/fimmu.2018.00018