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Inverse Modulation of Neuronal K(v)12.1 and K(v)11.1 Channels by 4-Aminopyridine and NS1643

The three members of the ether-à-go-go-gene-like (Elk; K(v)12.1-K(v)12.3) family of voltage-gated K(+) channels are predominantly expressed in neurons, but only little information is available on their physiological relevance. It was shown that K(v)12.2 channels modulate excitability of hippocampal...

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Detalles Bibliográficos
Autores principales: Dierich, Marlen, Evers, Saskia, Wilke, Bettina U., Leitner, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797642/
https://www.ncbi.nlm.nih.gov/pubmed/29440988
http://dx.doi.org/10.3389/fnmol.2018.00011