Inhibition of Glucose-6-Phosphate Dehydrogenase Reverses Cisplatin Resistance in Lung Cancer Cells via the Redox System

The pentose phosphate pathway (PPP), which branches from glycolysis, is correlated with cancer cell proliferation, survival and senescence. In this study, differences in the metabolic profile of the PPP and the redox status of human lung carcinoma A549 cells and cisplatin-induced multidrug-resistant...

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Detalles Bibliográficos
Autores principales: Hong, Weipeng, Cai, Peiheng, Xu, Chuncao, Cao, Di, Yu, Weibang, Zhao, Zhongxiang, Huang, Min, Jin, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797786/
https://www.ncbi.nlm.nih.gov/pubmed/29445340
http://dx.doi.org/10.3389/fphar.2018.00043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797786/
https://www.ncbi.nlm.nih.gov/pubmed/29445340
http://dx.doi.org/10.3389/fphar.2018.00043

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