Cargando…

Regulation of c‐MYC transcriptional activity by transforming growth factor‐beta 1‐stimulated clone 22

c‐MYC stimulates cell proliferation through the suppression of cyclin‐dependent kinase (CDK) inhibitors including P15 (CDKN2B) and P21 (CDKN1A). It also activates E‐box‐mediated transcription of various target genes including telomerase reverse transcriptase (TERT) that is involved in cellular immor...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Ling, Suzuki, Hiroyuki, Nakajo, Yuka, Nakano, Akinobu, Kato, Mitsuyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797808/
https://www.ncbi.nlm.nih.gov/pubmed/29224245
http://dx.doi.org/10.1111/cas.13466