Synthesis, characterization and in vitro release performance of the pegylated valnemulin prodrug

Valnemulin, successfully developed by Sandoz in 1984, is a new generation derivative of pleuromutilin related to tiamulin. Valnemulin has low water-solubility, a short half-life period, low bioavailability, and instability. The application of valnemulin was restricted. Therefore, finding a more mode...

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Detalles Bibliográficos
Autores principales: DONG, Xinrui, SHU, Xueye, WANG, Yingnan, NIU, Zhaohuan, XU, Shixia, ZHANG, Yue, ZHAO, Shuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797878/
https://www.ncbi.nlm.nih.gov/pubmed/29187697
http://dx.doi.org/10.1292/jvms.17-0434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797878/
https://www.ncbi.nlm.nih.gov/pubmed/29187697
http://dx.doi.org/10.1292/jvms.17-0434

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