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Population Pharmacokinetic Modeling of a Desmopressin Oral Lyophilisate in Growing Piglets as a Model for the Pediatric Population

Desmopressin is used to treat primary nocturnal enuresis in children. Over the years, various formulations of desmopressin were commercialized of which the sublingual melt tablet is preferred in the pediatric population, despite the lack of full PK studies in this population. A full PK study was per...

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Detalles Bibliográficos
Autores principales: Gasthuys, Elke, Vermeulen, An, Croubels, Siska, Millecam, Joske, Schauvliege, Stijn, van Bergen, Thomas, De Bruyne, Pauline, Vande Walle, Johan, Devreese, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797931/
https://www.ncbi.nlm.nih.gov/pubmed/29445339
http://dx.doi.org/10.3389/fphar.2018.00041