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Population Pharmacokinetic Modeling of a Desmopressin Oral Lyophilisate in Growing Piglets as a Model for the Pediatric Population
Desmopressin is used to treat primary nocturnal enuresis in children. Over the years, various formulations of desmopressin were commercialized of which the sublingual melt tablet is preferred in the pediatric population, despite the lack of full PK studies in this population. A full PK study was per...
Autores principales: | Gasthuys, Elke, Vermeulen, An, Croubels, Siska, Millecam, Joske, Schauvliege, Stijn, van Bergen, Thomas, De Bruyne, Pauline, Vande Walle, Johan, Devreese, Mathias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797931/ https://www.ncbi.nlm.nih.gov/pubmed/29445339 http://dx.doi.org/10.3389/fphar.2018.00041 |
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