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Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment

Mitotic spindles assemble from two centrosomes, which are major microtubule‐organizing centers (MTOCs) that contain centrioles. Meiotic spindles in oocytes, however, lack centrioles. In mouse oocytes, spindle microtubules are nucleated from multiple acentriolar MTOCs that are sorted and clustered pr...

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Detalles Bibliográficos
Autores principales: Bennabi, Isma, Quéguiner, Isabelle, Kolano, Agnieszka, Boudier, Thomas, Mailly, Philippe, Verlhac, Marie‐Hélène, Terret, Marie‐Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797964/
https://www.ncbi.nlm.nih.gov/pubmed/29330318
http://dx.doi.org/10.15252/embr.201745225