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Molecular Correlates of In Vitro Responses to Dacomitinib and Afatinib in Bladder Cancer

BACKGROUND: The HER family of proteins (EGFR, HER2, HER3 and HER4) have long been thought to be therapeutic targets for bladder cancer, but previous clinical trials targeting these proteins have been disappointing. Second generation agents may be more effective. OBJECTIVE: The aim of this study was...

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Detalles Bibliográficos
Autores principales: Tamura, Shuzo, Wang, Yin, Veeneman, Brendan, Hovelson, Daniel, Bankhead, Armand, Broses, Luke J., Lorenzatti Hiles, Guadalupe, Liebert, Monica, Rubin, John R., Day, Kathleen C., Hussain, Maha, Neamati, Nouri, Tomlins, Scott, Palmbos, Philip L., Grivas, Petros, Day, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798519/
https://www.ncbi.nlm.nih.gov/pubmed/29430509
http://dx.doi.org/10.3233/BLC-170144