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Molecular and Clinical Insights into the Role and Significance of Mutated DNA Repair Genes in Bladder Cancer

DNA damage response and repair genes (DDR genes) are commonly mutated in bladder cancer. The biological impact of these mutations is an area of intense basic, translational, and clinical interest. As next generation sequencing increases its foothold in the treatment of localized and advanced bladder...

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Detalles Bibliográficos
Autores principales: Abbosh, Philip H., Plimack, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798524/
https://www.ncbi.nlm.nih.gov/pubmed/29430503
http://dx.doi.org/10.3233/BLC-170129