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The Relevance of Iron in the Pathogenesis of Multiple System Atrophy: A Viewpoint

Iron is essential for cellular development and maintenance of multiple physiological processes in the central nervous system. The disturbance of its homeostasis leads to abnormal iron deposition in the brain and causes neurotoxicity via generation of free radicals and oxidative stress. Iron toxicity...

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Detalles Bibliográficos
Autores principales: Kaindlstorfer, Christine, Jellinger, Kurt A., Eschlböck, Sabine, Stefanova, Nadia, Weiss, Günter, Wenning, Gregor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798525/
https://www.ncbi.nlm.nih.gov/pubmed/29376857
http://dx.doi.org/10.3233/JAD-170601