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Nanoemulsion as a strategy for improving the oral bioavailability and anti-inflammatory activity of andrographolide

BACKGROUND: Andrographolide (AG), a compound with low water solubility, possesses various pharmacological activities, particularly anti-inflammatory activity. However, its low oral bioavailability is a major obstacle to its potential use. This study developed and optimized an AG-loaded nanoemulsion...

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Detalles Bibliográficos
Autores principales: Yen, Ching-Chi, Chen, Yi-Chen, Wu, Ming-Tsang, Wang, Chia-Chi, Wu, Yu-Tse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798547/
https://www.ncbi.nlm.nih.gov/pubmed/29440893
http://dx.doi.org/10.2147/IJN.S154824