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Associations between ABCG2 gene polymorphisms and gefitinib toxicity in non-small cell lung cancer: a meta-analysis

BACKGROUND: Gefitinib is frequently used to treat patients with non-small cell lung cancer (NSCLC) and is excreted out from cells via the ATP-binding cassette transporter ABCG2. ABCG2 gene polymorphisms have been suggested to be associated with ABCG2 protein expression and function and may influence...

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Detalles Bibliográficos
Autores principales: Tang, Lina, Zhang, Chunling, He, Hairong, Pan, Zhenyu, Fan, Di, He, Yinli, You, Haisheng, Li, Yuanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798561/
https://www.ncbi.nlm.nih.gov/pubmed/29440914
http://dx.doi.org/10.2147/OTT.S154244