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Role of MLH1 methylation in esophageal cancer carcinogenesis and its clinical significance

The mutL homolog-1 (MLH1) is a DNA mismatch repair gene and has been reported to be frequently methylated in numerous cancers. However, the association between MLH1 methylation and esophageal cancer (EC), as well as its clinical significance, remains unclear. Hence, we conducted a systematic meta-an...

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Detalles Bibliográficos
Autores principales: Li, Jinyun, Ye, Dong, Wang, Lei, Peng, Yingying, Li, Qun, Deng, Hongxia, Zhou, Chongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798571/
https://www.ncbi.nlm.nih.gov/pubmed/29440913
http://dx.doi.org/10.2147/OTT.S154999